References
REFERENCES

REFERENCES

Almond Nutrition Research: State of the Science (Updated August 2015)

Allergens

Chhabra GS, Liu C, Su M, Venkatachalam M, Roux KH, Sathe SK. 2017. Effects of the Maillard Reaction on the immunoreactivity of amandin in food matrices. Journal of Food Science. 82(10):2495-2503. Abstract Available via PubMed.

Liu C, Chhabra GS, Zhao J, Zaffran VD, Gupta S, Roux KH, Gradziel TM, Sathe SK. 2017. Comparison of Laboratory-Developed and Commercial Monoclonal Antibody-Based Sandwich Enzyme-Linked Immunosorbent Assays for Almond (Prunus dulcis) Detection and Quantification. Journal of Food Science. 82(10):2504-2515. Abstract Available via PubMed.

Su, M., M. Venkatachalam, T.M. Gradziel, C. Liu, Y. Zhang, K.H. Roux, S.K. Sathe. 2015. Application of mouse monoclonal antibody (mAb) 4C10-based enzyme-linked immunosorbent assay (ELISA) for amandin detection in almond (Prunus dulcis L.) genotypes and hybrids. Food Sci. Tech. 60:535-543. Abstract

Dhakal, S., C. Liu, Y. Zhang, K.H. Roux, S.K. Sathe, V.M. Balasubramaniam. 2014. Effect of high pressure processing on the immunoreactivity of almond milk. Food Res. Int. 62:215 -222. Abstract

Mandalari, G., N.M. Rigby, C. Bisignano, R.B. Lo Curto, F. Mullholland, M. Su, M. Venkatachalam, J.M. Robotham, L.N. Willison, K. Lapsley, K.H. Roux, S.K. Sathe. 2014. Effect of food matrix and processing on release of almond protein during simulated digestion. Food Sci. Tech. 59:439-447. Abstract

Su. M., M. Venkatachalam, C. Liu, Y. Zhang, K.H. Roux, S.K. Sathe. 2013. A murine monoclonal antibody based enzyme-linked immunosorbent assay for almond (Prunus dulcis L.) detection. J. Agric. Food Chem. 61:10823-10833. Abstract Available via PubMed

Willison, L.N., Q. Zhang, M. Su, S.S. Teuber, S.K. Sathe, K.H. Roux. 2013. Conformational epitope mapping of Pru du 6, a major allergen from almond nut. Mol. Immunol. 55(3-4):253-263. Abstract Available via PubMed

Kshirsagar, H.H., P. Fajer, G.M. Sharma, K.H. Roux, S.K. Sathe. 2011. Biochemical and spectroscopic characterization of almond and cashew nut seed 11S legumins, amandin and anacardein. J. Agric. Food Chem. 59:386-393. Abstract Available via PubMed

Willison, L.N., P. Tripathi, G. Sharma, S.S. Teuber, S.K. Sathe, K.H. Roux. 2011. Cloning, Expression and Patient IgE Reactivity of Recombinant Pru du 6, an 11S Globulin from Almond. Int. Arch. Allergy Immunol. 156(3):267-281. Abstract Available via PubMed

Tiwari, R.S., M. Venkatachalam, G.M. Sharma, M. Su, K.H. Roux, S.K. Sathe. 2010. Effect of food matrix on amandin, almond (Prunus dulcis L.) major protein, immunorecognition and recovery. Lwt - Food Science And Technology 43:675-683. Abstract

Su, M., M. Venkatachalam, S.S. Teuber, K.H. Roux, S.K. Sathe. 2004. Impact of γ-irradiation and thermal processing on the antigenicity of almond, cashew nut and walnut proteins. J. Sci. Food Agric 84:1119-1125. Abstract

Sathe, S.K., W.J. Wolf, K.H. Roux, S.S. Teuber, M. Venkatachalam, K.W.C. Sze-Tao. 2002. Biochemical characterization of amandin, the major storage protein in almond (Prunus dulcis L.). J. Agric. Food Chem. 50(15):4333-4341. Abstract Available via PubMed

Venkatachalam, M., S.S. Teuber, K.H. Roux, S.K. Sathe. 2002. Effects of roasting, blanching, autoclaving, and microwave heating on antigenicity of almond (Prunus dulcis L.) proteins. J. Agric. Food Chem. 50(12):3543-3548. Abstract Available via PubMed

Roux, K.H., S.S. Teuber, J.M. Robotham, S.K. Sathe. 2001. Detection and stability of the major almond allergen in foods. J. Agric. Food Chem. 49:2131-2136. Abstract Available via PubMed

Sathe, S.K., S.S. Teuber, T.M. Gradziel, K.H. Roux. 2001. Electrophoretic and immunological analyses of almond (Prunus dulcis L.) genotypes and hybrids. J. Agric. Food Chem. 49(4):2043-2052. Abstract Available via PubMed

Sze-Tao, K.W.C., S.K. Sathe. 2000. Functional properties and in vitro digestibility of almond (Prunus dulcis L.) protein isolate. Food Chem. 69:153-160. Abstract

Acosta, M.R., K.H. Roux, S.S. Teuber, S.K. Sathe. 1999. Production and characterization of rabbit polyclonal antibodies to almond (Prunus amygdalus L) major storage protein. J. Agric. Food Chem. 47:4053-4059. Abstract

Wolf, W.J., S.K. Sathe. 1998. Ultracentrifugal and polyacrylamide gel electrophoretic studies of extractability and stability of almond meal proteins. J. Agric. Food Chem. 78:511-521. Abstract

Composition

Duong QH, Clark KD, Lapsley KG, Pegg RB. 2017. Quantification of inositol phosphates in almond meal and almond brown skins by HPLC/ESI/MS. Food Chemistry. 229:84-92. Abstract Available via PubMed.

Bolling, BW. 2017. Almond polyphenols: Methods of analysis, contribution to food quality, and health promotion. Comprehensive Reviews in Food Science and Food Safety. 16(3):346-368. Available via Open Access.

Smeriglio A, Mandalari G, Bisignano C, Filocamo A, Barreca D, Bellocco E, Trombetta D. 2016. Polyphenolic content and biological properties of Avola almond (Prunus dulcis Mill. D.A. Webb) skin and its industrial byproducts. Industrial Crops and Products. 83:283-293. Abstract Available via ScienceDirect.

Xie, L., B.W. Bolling. 2014. Characterization of stilbenes in California almonds (Prunus dulcis) by UHPLC-MS. Food Chem. 148:300-306. Abstract Available via PubMed

Xie, L., A.V. Roto, B.W. Bolling. 2013. Characterization of ellagitannins, gallotannins, and bound proanthocyanidins from California almond (Prunus dulcis) varieties. J. Agric.Food Chem. 60(49):12151-12156. Abstract Available via PubMed

Yada, S., K. Lapsley, G. Huang. 2011. A review of composition studies of cultivated almonds: Macronutrients and micronutrients. J. Food Comp. Anal. 24:469-480. Abstract Available via PubMed

Bolling, B.W., G. Dolnikowski, J.B. Blumberg, C.-Y.O. Chen. 2010. Polyphenol content and antioxidant activity of California almonds depend on cultivar and harvest year. Food Chem. 122:819-825. Available via Open Access

Bolling, B.W., J.B. Blumberg, C.-Y.O. Chen. 2010. The influence of roasting, pasteurisation, and storage on the polyphenol content and antioxidant capacity of California almond skins. Food Chem. 123:1040-1047. Abstract

Mandalari, G., A. Tomaino, T. Arcoraci, M. Martorana, V. Lo Turco, F. Cacciola, G.T. Rich, C. Bisignano, A. Saija, P. Dugo, K.L. Cross, M.L. Parker, K.W. Waldron, M.S.J. Wickham. 2010. Characterization of polyphenols, lipids and dietary fibre from almond skins (Amygdalus communis L.). J. Food Comp. Anal. 23:166-174.

Mandalari, G., C. Bisignano, M. D'Arrigo, G. Ginestra, A. Arena, A. Tomaino, M.S.J. Wickham. 2010. Antimicrobial potential of polyphenols extracted from almond skins. Lett. Appl. Microbiol. 51(1):1-7. Available via Open Access

Bolling, B.W, G. Dolnikowski, J.B. Blumberg, C.-Y.O. Chen. 2009. Quantification of almond skin polyphenols by liquid chromatography-mass spectrometry. J. Food Sci. 74(4):C326 -C332. Available via Open Access

Chen, C.-Y., J.B. Blumberg. 2008. In vitro activity of almond skin polyphenols for scavenging free radicals and inducing quinone reductase. J. Agric. Food Chem. 56(12):4427-4434. Abstract Available via PubMed

Sathe, S.K., N.P. Seeram, H.H. Kshirsagar, D. Heber, K.A. Lapsley. 2008. Fatty acid composition of California grown almonds. J. Food Sci. 73(9):C607-C614. Available via Open Access

Chen, C.-Y., P.E. Milbury, S.-K. Chung, J. Blumberg. 2007. Effect of almond skin polyphenols and quercetin on human LDL and apolipoprotein. B-100 oxidation and conformation. J. Nutr. Biochem. 18:785-794.  Abstract Available via PubMed

Li, N., X. Jia, C.-Y.O. Chen, J.B. Blumberg, Y. Song, W. Zhang, X. Zhang, G. Ma, J. Chen. 2007. Almond consumption reduces oxidative DNA damage and lipid peroxidation in male smokers. J. Nutr. 137:2717-2722. Available via Open Access

Jia, X., N. Li, W. Zhang, X. Zhang, K. Lapsley, G. Huang, J. Blumberg, G. Ma, J. Chen. 2006. A pilot study on the effects of almond consumption on DNA damage and oxidative stress in smokers. Nutr. Cancer 54(2):179-183. Abstract Available via PubMed

Milbury, P.E., C.-Y. Chen, G.G. Dolnikowski, J.B. Blumberg. 2006. Determination of flavonoids and phenolics and their distribution in almonds. J. Agric. Food Chem. 54:5027-5033. Abstract Available via PubMed

Wijeratne, S.S.K., M.M. Abou-Zaid, F. Shahidi. 2006. Antioxidant polyphenols in almond and its coproducts. J. Agric. Food Chem. 54:312-318. Abstract Available via PubMed

Wijeratne, S.S.K., R. Amarowicz, F. Shahidi. 2006. Antioxidant activity of almonds and their by-products in food model systems. J. Am. Oil Chem. Soc. 83(3):223-230. Abstract

Amarowicz, R., T. Agnieszka, A. Troszynska, F. Shahidi. 2005. Antioxidant activity of almond seed extract and its fractions. J. Food Lipids 12:344-358. Abstract

Chen, C.-Y., P.E. Milbury, K.G. Lapsley, J.B. Blumberg. 2005. Flavonoids from almond skins are bioavailable and act synergistically with Vitamins C and E to enhance hamster and human LDL resistance to oxidation. J. Nutr. 135:1366-1373. Available via Open Access

Sang, S., G. Li, S. Tian, K. Lapsley, R.E. Stark, R.K. Pandey, R.T. Rosen, C.-T. Ho. 2003. An unusual diterpene glycoside from the nuts of almond (Prunus amygdalus Batsch). Tetrahedron Lett. 44:1199-1202. Abstract

Frison, S., P. Sporns. 2002. Variation in the flavonol glycoside composition of almond seedcoats as determined by MALDI-TOF mass spectrometry. J. Agric. Food Chem. 50 (23):6818-6822. Abstract Available via PubMed

Frison-Norrie, S., P. Sporns. 2002. Identification and quantification of flavonol glycosides in almond seedcoats using MALDI-TOF MS. J. Agric. Food Chem. 50(10):2782-2787. Abstract Available via PubMed

Milbury, P.E., C.-Y. Chen, H.-K. Kwak, J.B. Blumberg. 2002. Almond skins polyphenolics act synergistically with α-tocopherol to increase the resistance of low-density lipoproteins to oxidation. Free Radical Res. 36(1):78-80. Abstract Available via Scribd

Sang, S., X. Cheng, H.-Y. Fu, D.-E. Shieh, N. Bai, K.G. Lapsley, R.E. Stark, R.T. Rosen, C.-T. Ho. 2002. New type sesquiterpene lactone from almond hulls (Prunus amygdalus Batsch). Tetrahedron Lett. 43:2547-2549. Abstract Available via PubMed

Sang, S., K.G. Lapsley, W.S. Jeong, P.A. Lachance, C.-T. Ho, R.T. Rosen. 2002. Antioxidative phenolic compounds isolated from almond skins (Prunus amygdalus Batsch). J. Agric. Food Chem. 50(8):2459-2463. Abstract

Sang, S., H. Kikuzaki, K. Lapsley, R.T. Rosen, N. Nakatani, C.-T. Ho. 2002. Sphingolipid and other constituents from almond nuts (Prunus amygdalus Batsch). J. Agric. Food Chem. 50(16):4709-4712. Abstract Available via PubMed

Sang, S., K.G. Lapsley, R.T. Rosen, C.-T. Ho. 2002. New prenylated benzoic acid and other constituents from almond hulls (Prunus amygdalus Batsch). J. Agric. Food Chem. 50(3):607-609. Abstract Available via PubMed

Siriwardahana, S.S.K.W., F. Shahidi. 2002. Antiradical activity of extracts of almond and its by-products. J. Amer. Oil Chem. Soc. 79(9):903-908. Abstract

Diabetes + Metabolic Syndrome

Chen CM, Liu JF, Li SC, Huang CL, Hsirh AT, Chang ML, Li HT, Mohn E, Chen CO. 2017. Almonds ameliorate glycemic control in Chinese patients with better controlled type 2 diabetes: a randomized, crossover, controlled feeding trial. Nutrition & Metabolism. 14:51. Available via Open Access.

Gulati S, Misra A, Pandey RM. 2017. Effect of almond supplementation on glycemia and cardiovascular risk factors in Asian Indians in North India with type 2 diabetes mellitus: a 24-week study. Metabolic Syndrome and Related Disorders. 15(2):98-105. Available via Open Access.

Beatrice, A., G. Shivaji. 2015. Effect of almond supplementation on the anthropometric measurements, biochemical parameters and blood pressure levels of men with Metabolic Syndrome. Indian Journal of Nutrition and Dietetics 52(2):184-191.

Sweazea, K.L., C.S. Johnston, K.D. Ricklefs, K.N. Petersen. 2014. Almond supplementation in the absence of dietary advice significantly reduces C-reactive protein in subjects with type 2 diabetes J. Funct. Foods 10:252-259.

Liu, J.-F., Y.-H. Liu, C.-M. Chen, W.-H. Chang, C.-Y. O. Chen. 2013. The effect of almonds on inflammation and oxidative stress in Chinese patients with type 2 diabetes mellitus: a randomized crossover feeding trial. Eur. J. Nutr. 52:927-935. Abstract Available via PubMed

Kamil, A., C.-Y. O. Chen. 2012. Health benefits of almonds beyond cholesterol reduction. J. Agric. Food Chem. 60(27):6694-6702. Abstract Available via PubMed

Cohen, A.E., C.S. Johnston. 2011. Almond ingestion at mealtime reduces postprandial glycemia and chronic ingestion reduces hemoglobin A1c in individuals with well controlled type 2 diabetes mellitus. Metabolism 60(9):1312-1317. Abstract Available via PubMed

Li, S.-C., Y.-H. Liu, J.-F. Liu, W.-H. Chang, C.-M. Chen, C.-Y.O. Chen. 2011. Almond consumption improved glycemic control and lipid profiles in patients with type 2 diabetes mellitus. Metab. Clin. Exp. 60:474-479. Abstract Available via PubMed

Mori, A.M., R.V. Considine, R.D. Mattes. 2011. Acute and second-meal effects of almond form in impaired glucose tolerant adults: a randomized crossover trial. Nutr. & Metab. 8 (6):1-8. Abstract Available via PubMed

Mori, A., K. Lapsley, R.D. Mattes. 2011. Chapter 19. Almonds (Prunus dulcis): Post-Ingestive Hormonal Response. Nuts & Seeds In Health And Disease Prevention In V. R.

Preedy, R. R. Watson, V. B. Patel (Editors), Nuts & Seeds in Health and Disease Prevention (1st ed.) (pp.167-173).

Wien, M., D. Bleich, M. Raghuwanshi, S. Gould-Forgerite, J. Gomes, L. Monahan-Couch, K. Oda. 2010. Almond consumption and cardiovascular risk factors in adults with prediabetes J. Am. Coll. Nutr. 29(3):189-197. Abstract Available via PubMed

Josse, A.R., C.W.C. Kendall, L.S.A. Augustin, P.R. Ellis, D.J.A. Jenkins. 2007. Almonds and postprandial glycemia – a dose-response study. Metabolism 56:400-404. Abstract Available via PubMed

Jenkins D.J.A., C.W.C. Kendall, A.R. Josse, S. Salvatore, F. Brighenti, L.S.A. Augustin, P.R. Ellis, E. Vidgen, A.V. Rao. 2006. Almonds decrease postprandial glycemia, insulinemia and oxidative damage in healthy individuals. J. Nutr. 136:2987-2992. Available via Open Access

Scott, L.W., A. Balasubramanyam, K.T. Kimball, A.K. Aherns, C.M. Fordis, Jr., C.M. Ballantyne. 2003. Long-term, randomized clinical trial of two diets in the metabolic syndrome and type 2 diabetes. Diabetes Care 26(8):2481-2482. Abstract Available via PubMed

Lovejoy, J.C., M.M. Most, M. Lefevre, F.L. Greenway, J.C. Rood. 2002. Effect of diets enriched in almonds on insulin action and serum lipids in adults with normal glucose tolerance or type 2 diabetes. Am. J. Clin. Nutr. 76:1000-1006. Available via PubMed

Heart Health

Jung H, Chen CO, Blumberg JB, Kwak HK. 2017. The effect of almonds on vitamin E status and cardiovascular risk factors in Korean adults: a randomized clinical trial. European Journal of Nutrition. Jul 10. doi: 10.1007/s00394-017-1480-5. Available via Open Access.

Berryman CE, Fleming JA, Kris-Etherton PM. 2017. Inclusion of almonds in a cholesterol-lowering diet improves plasma HDL subspecies and cholesterol efflux to serum in normal-weight individuals with elevated LDL cholesterol. Journal of Nutrition. 147(8):1517-1523. Available via Open Access.

Musa-Veloso K, Paulionis L, Poon T, Lee H-Y. The effects of almond consumption on fasting blood lipid levels: a systematic review and meta-analysis of randomized controlled trials. Journal of Nutritional Science. 2016;5(e34):1-15. Available Via Open Access

Berryman CE, West SG, Fleming JA, Bordi PL, Kris-Etherton PM. Effects of Daily Almond Consumption on Cardiometabolic Risk and Abdominal Adiposity in Healthy Adults With Elevated LDL-Cholesterol: A Randomized Controlled Trial Journal of the American Heart Association. 2015;4(1): e000993. Available Via Open Access

Chen, C.-Y., M. Holbrook, M.-A. Duess, M. M. Dohadwala, N.M. Hamburg, B.F. Asztalos, P.E. Milbury, J.B. Blumberg, J.A. Vita. 2015. Effect of almond consumption on vascular function in patients with coronary artery disease: a randomized, controlled, cross-over trial. Nutrition Journal 14(61):1-11. Available Via Open Access

Ruisinger, J.F., C.A. Gibson, J.M. Backes, B.K. Smith, D.K. Sullivan, P.M. Moriarty, P. Kris-Etherton. 2015. Statins and almonds to lower lipoproteins (the STALL Study) J. Clin. Lipid. 9:58-64. Available Via Open Access

Nishi, S., C.W.C. Kendall, A.-M. Yoon, R.P. Bazinet, B. Bashyam, K.G. Lapsley, D.J.A. Jenkins. 2014. Effect of almond consumption on the serum fatty acid profile: a dose response study. Br. J. Nutr. 112(2):1137-1146. Abstract Available via PubMed

Berryman, C.E., A.G. Preston, W. Karmally, R.J. Deckelbaum, P.M. Kris-Etherton. 2011. Effects of almond consumption on the reduction of LDL-cholesterol: a discussion of potential mechanisms and future research directions. Nutrition Reviews 69(4):171-185. Abstract Available via PubMed

Jaceldo-Siegl, K., J. Sabate, M. Batech, G.E. Fraser. 2011. Influence of body mass index and serum lipids on the cholesterol-lowering effects of almonds in free-living individuals. Nutr. Metab. Cardiovasc. Dis. 21:S7-S13. Abstract Available via PubMed

Rajaram, S., K.M. Connell, J. Sabate. 2010. Effect of almond-enriched high monounsaturated fat diet on selected markers of inflammation: a randomized, controlled, crossover study Br. J. Nutr. 103:907-912. Abstract Available via PubMed

Berry, S.E.E., E.A. Tydeman, H.B. Lewis, R. Phalora, J. Rosborough, D.R. Picout, P.R. Ellis. 2008. Manipulation of lipid bioaccessibility of almond seeds influences postprandial lipemia in healthy human subjects. Am. J. Clin. Nutr. 88:922-929. Available Via Open Access

Jenkins, D.J.A., C.W.C. Kendall, A. Marchie, A.R. Josse, T.H. Nguyen, D.A. Faulkner, K.G. Lapsley, J. Blumberg. 2008. Almonds reduce biomarkers of lipid peroxidation in older hyperlipidemic subjects. J. Nutr. 138:908-913. Available via Open Access

Jenkins, D.J.A., C.W.C. Kendall, A. Marchie, A.R. Josse, T.H. Nguyen, D.A. Faulkner, K.G. Lapsley, W. Singer. 2008. Effect of almonds on insulin secretion and insulin resistance in nondiabetic hyperlipidemic subjects: a randomized controlled crossover trial. Metab. Clin. Exp. 57:882-887. Abstract Available via PubMed

Gigleux, I., D.J.A. Jenkins, C.W.C. Kendall, A. Marchie, D.A. Faulkner, J.M.W. Wong, R. de Souza, A. Emam, T.L. Parker, E.A. Trautwein, K.G. Lapsley, P.W. Connelly, B. Lamarche. 2007. Comparison of a dietary portfolio diet of cholesterol-lowering foods and a statin on LDL particle size phenotype in hypercholesterolaemic participants. Br. J. Nutr. 98:1-8. Abstract Available via PubMed

Jenkins, D.J.A., C.W.C. Kendall, D.A. Faulkner, T. Kemp, A. Marchie, T.H. Nguyen, J.M.W. Wong, R. de Souza, A. Emam, E. Vidgen, E.A. Trautwein, K.G. Lapsley, R.G. Josse, L.A. Leiter, W. Singer. 2007. Long-term effects of a plant-based dietary portfolio of cholesterol-lowering foods on blood pressure. Eur. J. Clin. Nutr. 62:1-8. Abstract Available via PubMed

Jenkins, D.J.A., C.W.C. Kendall, D.A. Faulkner, T. Nguyen, T. Kemp, A. Marchie, J.M.W. Wong, R. de Souza, A. Emam, E. Vidgen, E.A. Trautwein, K.G. Lapsley, C. Holmes, R.G. Josse, L.A. Leiter, P.W. Connelly, W. Singer. 2006. Assessment of the longer-term effects of a dietary portfolio of cholesterol-lowering foods in hypercholesterolemia. Am. J. Clin. Nutr. 83:582-591. Available via Open Access

Jenkins, D.J.A., C.W.C. Kendall, T.H. Nguyen, J. Teitel, A. Marchie, M. Chiu, A.Y. Taha, D.A. Faulkner, T. Kemp, J.M.W. Wong, R. de Souza, A. Emam, E.A. Trautwein, K.G. Lapsley, C. Holmes, R.G. Josse, L.A. Leiter, W. Singer. 2006. Effect on hematologic risk factors for coronary heart disease of a cholesterol reducing diet. Eur. J. Clin. Nutr. 61:1-10. Abstract Available via PubMed

Jambazian, P.R, E. Haddad, S. Rajaram, J. Tanzman, J. Sabate. 2005. Almonds in the diet simultaneously improve plasma α-tocopherol concentrations and reduce plasma lipids. J. Am. Diet. Assoc. 105:449-454. Abstract Available via PubMed

Jenkins, D.J.A., C.W.C. Kendall, A. Marchie, D. Faulkner, J.M.W. Wong, R. de Souza, A. Emam, T.L. Parker, E. Vidgen, E.A. Trautwein, K.G Lapsley, R.G. Josse, L.A. Leiter, W. Singer, P.W. Connelly. 2005. Direct  comparison of a dietary portfolio of cholesterol lowering foods with a statin in hypercholesterolemic participants. Am. J. Clin. Nutr. 81:380-387. Available via Open Access

Jenkins, D.J.A., C.W.C. Kendall, A. Marchie, D.A. Faulkner, A.R. Josse, J.M.W. Wong, R. de Souza, A. Emam, T.L. Parker, T.J. Li, R.G. Josse, L.A. Leiter, W. Singer, P.W. Connelly. 2005. Direct comparison of dietary portfolio vs statin on C-reactive protein. Eur. J. Clin. Nutr. 59:851-860. Abstract Available via PubMed

Lamarche, B., S. Desroches, D.J.A. Jenkins, C.W.C. Kendall, A. Marchie, D.A. Faulker, E. Vidgen, K.G. Lapsley, E.A. Trautwein, T.L. Parker, R.G. Josse, L. A. Leiter, P. W. Connelly. 2004. Combined effects of a dietary portfolio of plant sterols, vegetable protein, viscous fibre and almonds on LDL particle size. Br. J. Nutr. 92:657-663. Abstract Available via PubMed

Jenkins, D.J.A., C.W.C. Kendall, A. Marchie, D.A. Faulkner, J.M.W. Wong, R. de Souza, A. Emam, T.L. Parker, E. Vidgen, K.G. Lapsley, E.A. Trautwein, R.G. Josse, L.A. Leiter, P.W. Connelly. 2003. Effects of a dietary portfolio of cholesterol - lowering foods vs lovastatin on serum lipids and C-reactive protein. J. Am. Med. Assoc. 290(4):502-510. Abstract Available via PubMed

Jenkins, D.J.A., C.W.C. Kendall, A. Marchie, D. Faulkner, E. Vidgen, K.G. Lapsley, E.A. Trautwein, T.L. Parker, R.G. Josse, L.A. Leiter, P.W. Connelly. 2003. The effect of combining plant sterols, soy protein, viscous fibers, and almonds in treating hypercholesterolemia. Metabolism 52(11):1478-1483. Abstract Available via PubMed

Sabaté, J., E. Haddad, J.S. Tanzman, P. Jambazian, S. Rajaram. 2003. Serum lipid response to the graduated enrichment of a Step I diet with almonds: A randomized feeding trial. Am. J. Clin. Nutr. 77:1379-1384. Available via Open Access

Spiller, G.A., A. Miller, K. Olivera, J. Reynolds, B. Miller, S.J. Morse, A. Dewell, J.W. Farquhar. 2003. Effects of plant-based diets high in raw or roasted almonds, or roasted almond butter on serum lipoproteins in humans. J. Am. Coll. Nutr. 22(3):195-200. Abstract Available via PubMed

Hyson, D.A., B.O. Schneeman, P.A. Davis. 2002. Almonds and almond oil have similar effects on plasma lipids and LDL oxidation in healthy men and women. J. Nutr. 132:703-707. Available via Open Access

Jenkins, D.J.A., C.W.C. Kendall, A. Marchie, T.L. Parker, P.W. Connelly, W. Qian, J.S. Haight, D. Faulkner, E. Vidgen, K.G. Lapsley, G.A. Spiller. 2002. Dose response of almonds on coronary heart disease risk factors: blood lipids, oxidized low-density lipoproteins, lipoprotein(a), homocysteine, and pulmonary nitric oxide a randomized, controlled, crossover trial. Circulation 106:1327-1332. Available via Open Access

Xiao, Y., J.B. Wang, S.F. Yan, X.J. Lian, Y. Tang, and Y. Liu. 2002. The effects of nuts rich in monounsaturated fatty acids on the level of serum lipids in hyperlipidemia patients. China Public Health 18(8):931-932.(as translated from Chinese). Abstract Available via PubMed

Spiller, G.A., D.J.A. Jenkins, O. Bosello, J.E. Gates, L.N. Cragen, B. Bruce. 1998. Nuts and plasma lipids: An almond diet lowers LDL-C while preserving HDL-C. J. Am. Coll. Nutr. 17(3):285-290. Abstract Available via PubMed

Spiller, G.A., D.J.A. Jenkins, L.N. Cragen, J.E. Gates, O. Bosella, K. Berra, C. Rudd, M. Stevenson, R. Superko. 1992. Effect of a diet high in monounsaturated fat from almonds on plasma cholesterol and lipoproteins. J. Am. Coll. Nutr. 11(2):126-130. Abstract Available via PubMed
 

Weight Management, Satiety + Gut Health

Sayer RD, Dhillon J, Tamer GG, Cornier MA, Chen N, Wright A, Campbell W, Mattes RD. 2017. Consuming almonds vs. isoenergetic baked food does not differentially influence postprandial appetite or neural reward responses to visual food stimuli. Nutrients. 9(8):807. Available via Open Access.

Grassby T, Mandalari G, Grundy MML, et al. 2017. In vitro and in vivo modeling of lipid bioaccessibility and digestion from almond muffins: The importance of the cell-wall barrier mechanism. Journal of Functional Foods. 37:263-271. Available via Open Access.

Dhillon J, Tan SY, Mattes RD. 2016. Almond consumption during energy restriction lowers truncal fat and blood pressure in compliant overweight or obese adults. Journal of Nutrition. 146(12):2513-2519. Available via Open Access.

Gebauer SK, Novotny JA, Bornhorst GM, Baer DJ. 2016 Food processing and structure impact the metabolizable energy of almonds. Food & Function 7(10):4231-4238.  Available via Open Access

Bornhorst, G.M., K.C. Dreschsler, C.A. Montoya, S.M. Rutherfurd, P.J. Moughan, R.P. Singh. 2016. Gastric protein hydrolysis of raw and roasted almonds in the growing pig. Food Chem. 211:502-508. Abstract Available via PubMed

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Grundy, M.M.L., F. Carriere, A.R. Mackie, D.A. Gray, P.J. Butterworth, P.R Ellis. 2016. The role of plant cell wall encapsulation and porosity in regulating lipolysis during the digestion of almond seeds. Food & Function 7(1):69-78. Available Via Open Access

Grundy, M.M.-L., K. Lapsley, P.R. Ellis. 2016. A review of the impact of processing on nutrient bioaccessibility and digestion of almonds. Int. J. Food Sci .tech. doi:10.1111/ijfs.13192. Available Via Open Access

Liu, Z, W. Wang, G. Huang, W. Zhang and L. Ni. 2016. In vitro and in vivo evaluation of the prebiotic effect of raw and roasted almonds (Prunus amygdalus). J. Sci. Food Agric. DOI 10.1002/jsfa.7604. Available via Open Access

Dalton, M., S. Hollingworth, J. Blundell, G. Finlayson. 2015. Weak Satiety Responsiveness Is a Reliable Trait Associated with Hedonic Risk Factors for Overeating among Women. Nutrients 7:7421-7436. Available Via Open Access

Grundy, M.M.L., T. Grassby, G. Mandalari, KW Waldron, PF Butterworth, SEE Berry, PR Ellis. 2015. Effect of mastication on lipid bioaccessibility of almonds in a randomized human study and its implications for digestion kinetics, metabolizable energy, and postprandial lipemia. Am. J. Clin. Nutr. 101:25-33. Available Via Open Access

Grundy, M.M.L., P.J. Wilde, P.J. Butterworth, R. Gray, P.R. Ellis. 2015. Impact of cell wall encapsulation of almonds on in vitro duodenal lipolysis Food Chem. 185:405-412. Available Via Open Access

Hull, S., R. Re, L. Chambers, A. Echaniz, M.S.J. Wickham. 2015. A mid-morning snack of almonds generates satiety and appropriate adjustment of subsequent food intake in healthy women. Eur. J. Nutr. 54:803-810. Available Via Open Access

Grassby, T., D.R. Picout, G. Mandalari, R.M. Faulks, C.W.C. Kendall, G.T. Rich, M.S.J. Wickham, K. Lapsley, P.R. Ellis. 2014. Modelling of nutrient bioaccessibility in almond seeds based on the fracture properties of their cell walls. Food And Function 5(12):3096-3106. Abstract Available via PubMed

Liu, Z., X. Lin, G. Huang, W. Zhang, P. Rao, L. Ni. 2014. Prebiotic effects of almonds and almond skins on intestinal microbiota in healthy adult humans. Anaerobe 26:1-6. Abstract Available via PubMed

Mandalari, G., M.M.-L. Grundy, T. Grassby, M.L. Parker, K.L. Cross, S. Chessa, C. Gisignano, D. Barreca, E. Bellocco, G. Lagana, P.J. Butterworth, R.M. Faulks, P.J. Wilde, P.R. Ellis, K.W. Waldron. 2014. The effects of processing and mastication on almond lipid bioaccessibility using novel methods of in vitro digestion modelling and microstructural analysis. Br. J. Nutr. 112(9):1521-1529. Abstract Available via PubMed

Ukhanova, M., X. Wang, D.J. Baer, J.A. Novotny, M. Fredborg, V. Mai. 2014. Effects of almond and pistachio consumption on gut microbiota composition in a randomized cross-over human feeding study. Br. J. Nutr. 111(2):2146-2152. Abstract Available via PubMed

Bornhorst, G. M., M. J. Roman, S. M. Rutherfurd, B. J. Burri, P. J. Moughan, R.P. Singh. 2013. Gastric digestion of raw and roasted almonds in vivo. J. Food Sci. 78(11):H1807- H1813. Abstract Available via PubMed

Bornhorst, G.M., M.J. Roman, K.C. Dreschler, R.P. Singh. 2013. Physical property changes in raw and roasted almonds during gastric digestion In vivo and In vitro. Food Biophys. 9(1):39-48. Abstract Available via PubMed

Tan, S.-Y., R.D. Mattes. 2013. Appetitive, dietary and health effects of almonds consumed with meals or as snacks. Eur. J. Clin. Nutr. 67:1205-1214. Available Via Open Access

Foster, G.D., K.L. Shantz, S.S. Vander Veur, T.L. Oliver, M.R. Lent, A. Virus, P.O. Szapary, D. J. Rader, B.S. Zemel, A. Gilden-Tsai. 2012. A randomized trial of the effects of an almond enriched, hypocaloric diet in the treatment of obesity. Am. J. Clin. Nutr. 96(2):249-254. Available Via Open Access

Novotny, J.A., S. K. Gebauer, D.J. Baer. 2012. Discrepancy between the Atwater factor predicted and empirically measured energy values of almonds in human diets. Am. J. Clin. Nutr. 96(2):296-301. Available Via Open Access

Mandalari, G., R.M. Faulks, C. Bisignano, K.W. Waldron, A. Narbad, M.S.J. Wickham. 2010. In vitro evaluation of the prebiotic properties of almond skins (Amygdalus communis L.). Fems Microbiol. Lett. 304:116-122. Available Via Open Access

Mandalari, G., A. Tomaino, G.T. Rich, R. Lo Curto, T. Arcoraci, M. Martorana, C. Bisignano, A. Saija, M.L. Parker, K.W. Waldron, M.S.J. Wickham. 2010. Polyphenol and nutrient release from skin of almonds during simulated human digestion. Food Chem. 122:1083-1088. Available Via Open Access

Cassady, B.A., J.H. Hollis, A.D. Fulford, R.V. Considine, R.D. Mattes. 2009. Mastication of almonds: effects of lipid bioaccessibility, appetite, and hormone response. Am. J. Clin. Nutr. 89:794-800. Available Via Open Access

Mandalari, G., G.T. Rich, R.M. Faulks, C. Bisignano, A. Narbad, M.S.J. Wickham. 2009. Almonds demonstrate prebiotic potential effects of almond lipid on colonic microbiota. Agro Food Ind. Hi Tec. 20(3):47-49. Abstract

Frecka, J.M., J.H. Hollis, R.D. Mattes. 2008. Effects of appetite, BMI, food form and flavor on mastication: almonds as a test food. Eur. J. Clin. Nutr. 62:1231-1238. Abstract Available Via PubMed

Mandalari, G., R.M. Faulks, G.T. Rich, V.L. Turcos, D.R. Picout, R.B.L. Curto, G. Bisignano, G. Dugo, K.W. Waldron, P.R. Ellis, M.S.J. Wickham. 2008. Release of protein, lipid, and Vitamin E from almond seeds during digestion. J. Agric. Food Chem. 56(9):3409-3416. Abstract Available Via PubMed

Hollis, J., R. Mattes. 2007. Effect of chronic consumption of almonds on body weight in healthy humans. Br. J. Nutr. 98:651-656. Abstract Available Via PubMed

Burton-Freeman, B., P.A. Davis, B.O. Schneeman. 2004. Interaction of fat availability and sex on postprandial satiety and cholecystokinin after mixed-food meals. Am. J. Clin. Nutr. 80:1207-1214. Available Via Open Access

Ellis, P.R., C.W.C. Kendall, Y. Ren, C. Parker, J.F. Pacy, K.W. Waldron, D.J.A. Jenkins. 2004.

Role of cell walls in the bioaccessibility of lipids in almond seeds. Am. J. Clin. Nutr. 80:604-613. Available Via Open Access

Jaceldo-Siegl, K., J. Sabate, S. Rajaram, G.E. Fraser. 2004. Long-term almond supplementation without advice on food replacement induces favourable nutrient modifications to the habitual diets of free-living individuals. Br. J. Nutr. 92:533-540. Abstract Available Via PubMed

Wien, M.A., J.M. Sabate, D.N. Ikle, S.E. Cole, F.R. Kandeel. 2003. Almonds vs complex carbohydrates in a weight reduction program. Int. J. Obesity 27:1365-1372. Abstract Available Via PubMed

Fraser, G.E., H.W. Bennett, K.B. Jaceldo-Siegl, J. Sabaté. 2002. Effect on body weight of a free 76 kilojoule (320 calorie) daily supplement of almonds for six months. J. Am. Coll. Nutr. 21(3):275-283. Abstract Available Via PubMed

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Other

Dhillon J, Ferreira CR, Sobreira TJ, Mattes RD. 2017. Multiple reaction monitoring (MRM)-profiling to assess compliance with an almond consumption intervention. Current Developments in Nutrition. 1(9) e001545. Available via Open Access.

Bisignano C, Mandalari G, Smeriglio A, Trombetta D, Pizzo MM, Pennisi R, Sciortino MT. 2017. Almond skin extracts abrogate HSV-1 replication by blocking virus binding to the cell. Viruses. 9(7):178. Available via Open Access.

Rehm CD and Drewnowski A. 2017. Replacing American snacks with tree nuts increases consumption of key nutrients among US children and adults: results of an NHANES modeling study. Nutrition Journal. 16(1):17. Available via Open Access.

Dhillon J, Tan S-Y, Mattes RD. 2016. Effects of almond consumption on the post-lunch dip and short-term cognitive function in energy-restricted overweight and obese adults. British Journal of Nutrition. 117(3):395-402. Abstract Available via PubMed.

Mandalari, G., M. Vardakou, R. Faulks, C. Bisignano, M. Martorana, A. Smeriglio, D. Trombette. 2016. Food matrix effects of polyphenol bioaccessibility from almond skin during simulated human digestion. Nutrients 568; doi: 10.3390/nu8090568 Available Via Open Access

O'Neil, C.E., T.A. Nicklas, V.L. Fulgoni III. 2016. Almond consumption is associated with better nutrient intake, nutrient adequacy, and diet quality in adults: National Health and Nutrition Examination Survey 2001-2010 Food And Nutirition Sciences 7:504-515. Available Via Open Access

Chen, C.Y. 2014. Health benefits of almond consumption among Chinese consumers. (in Chinese). Chin. J. Prev. Med. 48(3):231-233.

Yi, M., J. Fu, L. Zhou, H. Gao, C. Fan, J. Shao, B. Xu, Q. Wang, J. Li, G. Huang, K. Lapsley, J.B. Blumberg, C.-Y.O Chen. 2014. The effect of almond consumption on elements of endurance exercise performance in trained athletes. J. Int. Soc. Sports Nutr. 11:18. Available Via Open Access

Bisignano, C., A. Filocamo, E. La Camera, S. Zummo, M.T. Fera, G. Mandalari. 2013. Antibacterial activities of almond skins on cagA-positive and-negative clinical isolates of Helicobacter pylori. Bmc Microbiol. 13:103. Abstract Available via PubMed

Evans-Johnson, J.A., Garlick, J.A., Johnson, E.J., Wang, X.-D., Chen, C.-Y.O.. 2013. A pilot study of the photoprotective effect of almond phytochemicals in a 3D human skin equivalent. Jour. Phytochem. And Phytobiol. 126:17-25. Abstract Available via PubMed

Mandalari, G., T. Arcoraci, M. Martorana, C. Bisignano, L. Rizza, F.P. Bonina, D. Trombetta, A. Tomaino. 2013. Antioxidant and photoprotective effects of blanch water, a byproduct of the almond processing industry. Molecules 18:12426-12440. Available via Open Access

Mandalari, G., T. Genovese, C. Bisignano, E. Mazzon, M.S.J. Wickham, R. Di Paola, G. Bisignano, S. Cuzzocrea. 2011. Neuroprotective effects of almond skins in experimental spinal cord injury. Clin. Nutr. 30:221-233. Abstract Available via PubMed

Mandalari, G., C. Bisignano, T. Genovese, E. Mazzon, M.S.J. Wickham, I. Paterniti, S. Cuzzocrea. 2011. Natural almond skin reduced oxidative stress and inflammation in an experimental model of inflammatory bowel disease. Int. Immunopharmacol. 11(8):915-924.